Rich, 100-300mA is a lot of current with the car locked!
My suggestion is a faulty alarm or immobiliser system with it being intermittent.
Check door, boot, glove box switches while monitoring the current drain.
Well done with a Fluke clamp-on!! Next a hand held infra-red camera.
A bit off topic, but the guy in the video is worth a look: https://www.bigjimny.com/index.php/f...adually#226090